What is HIPEC and How Does It Work?
HIPEC, or Hyperthermic Intraperitoneal Chemotherapy, is a specialized cancer treatment designed for patients with advanced abdominal cancers such as peritoneal carcinomatosis, ovarian cancer, colorectal cancer, and appendix tumors. Unlike traditional chemotherapy that is delivered intravenously, HIPEC involves the direct application of heated chemotherapy drugs into the abdominal cavity immediately after cytoreductive surgery (CRS).
During the procedure, surgeons first remove visible tumors through cytoreductive surgery and then circulate a heated chemotherapy solution (typically around 41–43°C) within the abdomen for approximately 90 minutes. This hyperthermic intraperitoneal chemotherapy targets microscopic cancer cells that may remain after surgery, increasing drug penetration and minimizing systemic side effects.
The heat not only enhances the effectiveness of the chemotherapy but also improves blood flow to the tissues, allowing for better absorption. HIPEC surgery in Turkey has become increasingly popular due to the expertise of surgical oncologists and the availability of cutting-edge facilities.
This treatment is often a last-resort but life-extending option for patients with otherwise limited choices, providing a targeted, aggressive approach while avoiding some of the side effects of systemic chemotherapy.
Who Are Candidates for HIPEC Surgery?
HIPEC is not suitable for every cancer patient; it is typically reserved for individuals diagnosed with cancers that have spread to the peritoneal surface. Patients with peritoneal carcinomatosis stemming from colorectal, gastric, ovarian, or appendiceal origins may be candidates, provided the disease is confined to the abdominal cavity and has not metastasized to distant organs like the lungs or brain.
Doctors use imaging scans (CT, MRI, PET) and diagnostic laparoscopy to evaluate whether a patient qualifies for HIPEC treatment. The decision often involves a multidisciplinary team including surgical oncologists, radiologists, and medical oncologists. Factors such as overall health, tumor type, extent of disease spread, and previous treatments are considered.
In Turkey, pre-operative evaluation for HIPEC surgery is performed thoroughly to ensure that patients are eligible for this highly specialized procedure. The patient selection process is critical, as outcomes largely depend on how complete the cytoreductive surgery can be.
International patients often choose HIPEC in Turkey not only because of the advanced expertise but also due to significantly reduced waiting times and more accessible specialist consultations.
Types of HIPEC Procedure
The HIPEC surgery procedure typically begins with cytoreductive surgery, during which the surgeon removes all visible tumors from the abdominal cavity. Once completed, the next phase involves the infusion of heated chemotherapy directly into the peritoneal cavity, targeting any microscopic cancer cells that remain. This dual approach is known as cytoreductive surgery and HIPEC.
There are several variations in how HIPEC is administered, depending on the cancer type, hospital protocols, and surgeon preference. Most commonly, a closed-technique method is used where the abdominal cavity is sealed, and the chemotherapy solution is circulated inside. In some specialized centers, an open-technique (Coliseum method) is preferred, allowing direct observation and manual agitation of the chemotherapy solution during circulation.
Hyperthermic intraperitoneal chemotherapy has been found especially effective in treating peritoneal surface malignancies such as pseudomyxoma peritonei, mesothelioma, and peritoneal carcinomatosis from colorectal or ovarian cancer. The goal is to deliver a high concentration of chemotherapy where it’s needed most, reducing exposure to the rest of the body.
Avicenna International Hospital offers advanced surgical oncology services including HIPEC surgery in Turkey, performed by experienced oncology teams using modern closed and open technique systems. This level of expertise ensures that each patient receives personalized, evidence-based treatment tailored to their condition.
Cost of HIPEC Surgery in Turkey
The cost of HIPEC surgery in Turkey can vary significantly depending on several factors such as the patient’s condition, duration of hospitalization, additional treatments (like imaging, pathology, or ICU stay), and hospital amenities. On average, patients can expect prices ranging from $10,000 to $20,000 for the entire HIPEC procedure in Turkey.
Compared to the United States or Western Europe, where the same treatment can exceed $50,000, choosing HIPEC surgery in Turkey offers a cost-effective alternative without compromising on quality. Many international patients benefit from affordable, world-class cancer treatment with shorter waiting times and multilingual care.
Avicenna International Hospital provides transparent treatment packages, and our medical consultants assist international patients in receiving pre-operative consultations, visa assistance, accommodation planning, and aftercare support. For accurate pricing tailored to your specific case, we recommend reaching out through our contact page.
To learn more about why so many people travel to Istanbul for complex oncology procedures, visit our page on Why Choose Turkey for Treatment.
HIPEC Recovery Timeline and Success Rate
Recovery after HIPEC surgery varies from patient to patient, but typically involves a hospital stay of 7–10 days, followed by several weeks of home recovery. During the initial post-operative period, patients are closely monitored for infection, bowel function, and response to the chemotherapy.
In the first month, fatigue and digestive issues are common, but these usually improve with time and supportive care. By the third month, most patients can gradually return to daily activities. Full recovery may take up to six months depending on the patient’s age, cancer type, and overall health status.
The success rate of HIPEC depends largely on the cancer type and how completely the visible tumors were removed during cytoreductive surgery. For selected cancers like appendiceal or colorectal origin, studies have shown five-year survival rates exceeding 50% when HIPEC is applied appropriately.
At our hospital, every patient undergoing HIPEC is supported by a dedicated care team, including surgical oncologists, ICU nurses, and rehabilitation staff to ensure optimal recovery outcomes. Our multidisciplinary approach helps ensure a smoother journey from surgery to survivorship.
Tips for Faster Recovery After HIPEC Surgery
Recovering after HIPEC surgery can vary from person to person, but following a structured post-operative plan significantly improves the healing process. Patients treated at Avicenna International Hospital often report faster recovery due to our comprehensive aftercare approach.
Nutrition, Hydration & Lifestyle
Maintaining a balanced, nutrient-rich diet is key to rebuilding strength. Focus on protein intake, fresh vegetables, and iron-rich foods. Hydration is just as essential—drink at least 2 liters of water daily unless restricted by your doctor. Patients often search for “nutrition after HIPEC surgery” or “diet for faster HIPEC recovery” to optimize their meal plans post-discharge.
Wound Care & Activity Level
Follow all wound-care instructions provided by your surgeon. Keep the incision site clean and dry, and watch for signs of infection. Early light activity such as walking is recommended to prevent blood clots and improve circulation. Queries like “early physical activity after HIPEC” are common among recovering patients.
Monitoring for Complications
Attend all follow-up appointments and report symptoms such as persistent fever, severe fatigue, or digestive issues. Monitoring helps avoid complications after HIPEC surgery, ensuring safer and faster recovery. Our clinical team is always available for guidance.
Is HIPEC Surgery in Turkey Safe?
Safety is a major concern for patients considering overseas treatment. HIPEC surgery in Turkey is performed in internationally accredited hospitals under the supervision of highly trained oncologists and surgical teams.
Our hospital adheres to strict infection control protocols, uses FDA-approved chemotherapeutic agents, and applies evidence-based guidelines for surgical oncology. We understand that choosing a hospital abroad is a big decision, and that’s why we emphasize transparent communication and personalized care.
In our facility, English-speaking medical coordinators assist patients throughout their treatment journey, from the first consultation to post-surgical care and recovery. This consistent support structure has made Turkey, and especially Istanbul, a trusted destination for advanced oncological treatments.
FAQs About HIPEC Surgery in Turkey
What is HIPEC treatment?
HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is a targeted cancer treatment that delivers heated chemotherapy directly into the abdomen following tumor-removal surgery.
How much does HIPEC surgery cost?
Prices vary based on individual medical needs, but Turkey offers more affordable rates compared to the US or UK. Our hospital provides personalized cost estimates for each patient.
Who qualifies for HIPEC treatment?
Eligibility depends on cancer type and spread. Patients with peritoneal-based cancers who haven’t developed distant metastasis may be considered.
Which hospitals offer HIPEC in Turkey?
A limited number of oncology centers in Turkey offer this advanced treatment. Our hospital is among the few providing expert-led HIPEC procedures.
Can you trust HIPEC surgery in Turkey?
Yes. With accredited hospitals, experienced surgeons, and high standards of care, Turkey is a reliable option for HIPEC treatment.
Take the First Step with Confidence
If you or a loved one has been diagnosed with abdominal cancer and you’re exploring advanced treatment options, we’re here to help. Our team is available to answer your questions, review your case, and guide you toward a personalized plan.
Click here to contact us or schedule a free video consultation with one of our surgical oncologists today.
